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Read More about this safari issue.Mississippi County may be known for its endless rows of cotton and historic role in the Arkansas Delta and American history, but it’s also home to some of the best eats in the state. From classic barbecue joints that have stood the test of time to new spots bringing fresh energy to the Arkansas food story, this corner of Arkansas is full of flavor and worth the drive.
Steel and Grain is one of Osceola’s newest dining options, serving big-city flavors in small-town Arkansas at the Holiday Inn. With a modern vibe and a menu that combines Southern comfort with creative flair, it has become popular among locals and tourists alike. The name reflects Mississippi County’s connections to agriculture and steel, but everyone knows it’s the food that keeps people coming back.
Fan Favorite: Fig Baguette, Chicken-fried Steak and Bourbon
316 W Hale Ave., Osceola
Website | Facebook
Situated on the town square, Wilson Cafe is a historic eatery in Delta that attracts visitors from all across Arkansas. The cafe offers elevated Southern cuisine, emphasizing locally sourced ingredients, all served within a beautifully restored historic building. With its stylish ambiance and farm-to-table philosophy, Wilson Cafe has helped put the small town of Wilson on the culinary map.
Fan Favorite: Heavenly Deviled Eggs and Fried Chicken, served with seasonal vegetables and a hot honey drizzle.
2 N Jefferson St., Wilson
Website | Facebook
Yank’s is a family-run spot that locals swear by for authentic Delta-style barbecue. The casual vibe and generous plates of smoked meats make it a must-visit for anyone hungry after exploring Blytheville’s museums or downtown. The aroma alone is enough to lure you in, but expect to walk up to the window and get your meal to go.
Fan Favorite: A slab of pork ribs, and don’t miss the slaw.
2100 W Main St., Blytheville
TripAdvisor
A true Arkansas icon, Kream Kastle has been serving barbecue and burgers since 1952. Although it may not look like much, this classic drive-in is a genuine part of Americana, offering a menu of comfort foods that never go out of style. People travel from all over the state just to dine here, making it one of Mississippi County’s most nostalgic food spots.
Fan Favorite: Pig Sandwich – a pulled pork barbecue sandwich with slaw. It’s the Delta; there’s just no other way.
112 N Division St., Blytheville
Encyclopedia Entry | Facebook
Dixie Pig is another legendary barbecue place that has been serving smoky delights for 100 years. Known for its relaxed atmosphere and hearty, satisfying dishes, Dixie Pig stays true to its roots. Generations of families have pulled up a chair here, and visitors enjoy the feeling of history in every bite.
Fan Favorite: Chopped pork sandwich with hot slaw; it’s the Delta way!
701 N 6th St., Blytheville
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If you love Arkansas barbecue, do not miss this list of the best bites around the state!
For those seeking something beyond barbecue, Olympia Steak and Seafood offers a diverse selection with a Cajun flair. This locally owned steakhouse provides a warm, inviting atmosphere and a menu featuring hearty options, including hand-cut steaks and fresh seafood dishes. It’s a place where a casual dinner can easily turn into a memorable night out.
Fan Favorite: Gator appetizer and grilled sea bass with Greek potatoes
122 W Main St., Blytheville
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With its relaxed river-town vibe, Sandbar Grille is the favorite spot in Osceola for great food and friendly service. The menu offers a wide range of options, from seafood to steaks, making it a versatile choice for lunch or dinner. Travelers love its laid-back atmosphere combined with Delta charm.
Fan Favorite: Fried catfish platter
1100 W Keiser Ave., Osceola
TripAdvisor
Sharks is a regional chain with a Blytheville location right off the highway that has won over locals with its crispy fried seafood and chicken, served quickly and fresh. It’s a casual spot perfect for grabbing a satisfying meal on the go, and the generous portions keep people coming back.
Fan Favorite: Fried catfish and shrimp combo. But they have gizzards and frog legs too!
109 N Service Rd., Blytheville
Facebook
The Hog Pen is a small-town barbecue spot with a loyal crowd. Known for its smoky meats and homemade sides, it reflects the Delta’s love for slow-cooked barbecue. The relaxed atmosphere makes it a perfect place to unwind and enjoy the flavors of Osceola.
Fan Favorite: Pulled pork nachos
2874 S US Highway 61, Osceola
Facebook
Tacker’s Shake Shack is a local favorite where nostalgia meets comfort food. Burgers, fries, and thick milkshakes are the staples here, and the friendly service makes it feel like home. Families and road trippers alike love this spot for a quick bite and a taste of classic Arkansas dining.
Fan Favorite: Cheeseburger with a chocolate shake.
490 AR-18 Bypass, Manila
Facebook
Don’t let the name fool you; Gunn’s is more than just a grocery store. This family-owned market is known for its fresh fried chicken and top-quality meats, including tomahawk steaks that are perfect for taking home or grilling right away. It’s a true hidden gem in Wilson.
Fan Favorite: Hot fried chicken straight from the deli.
13 Park Ave., Wilson
Facebook
With multiple locations across northeast Arkansas, 1812 Pizza Company has become a regional favorite for handcrafted pizzas. The Manila location offers creative pies filled with local flavors, as well as salads, pasta and wings. The relaxed, family-friendly atmosphere makes it an ideal spot for groups.
Fan Favorite: Cheesy Breadsticks and the All Pig Pie
639 AR-18 Bypass, Manila
Website | Facebook
From historic barbecue pits to modern farm-to-table dining, Mississippi County offers a food scene as rich as its history. Some of these restaurants have been serving travelers and locals for generations, their recipes rooted in Delta tradition, and their neon signs glowing like beacons for hungry road trippers. Others are newer spots redefining what it means to eat in small-town Arkansas, blending creativity with a strong sense of place.
Paired with the sights of Cotton Country, these meals turn a simple road trip into a journey through time and flavor. The Arkansas Delta is vibrant with taste, and Mississippi County is the ideal place to savor it.
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